Lymph nodes (2024)

Key facts

  • Lymph nodes (or lymph glands) are part of your body’s immune system.
  • The immune system helps to fight infections and filters waste products.
  • Your lymph nodes may swell up (lymphadenopathy) during an infection.
  • Common causes of swollen lymph nodes include viral and bacterial infections such as glandular fever and tonsillitis.
  • Your lymph nodes play an important role in cancer diagnosis, treatment, and your chance of recovery.

What are lymph nodes?

Your lymph nodes (or lymph glands) are small lumps of tissue that contain white blood cells, which fight infection. They are part of your body’s immune system. They filter your lymph fluid, which is composed of fluid and waste products created by the body’s tissues.

Lymph nodes help to fight infections. The glands near the infection can swell up (lymphadenopathy).

Where are my lymph nodes found?

Your lymph nodes are located throughout your body, including your:

  • neck and back (cervical lymph nodes)
  • armpits (axillary lymph nodes)
  • groin
  • stomach
  • chest

Your lymph nodes drain lymph fluid from your nearby organs and areas of your body.

What is the role of my lymph nodes?

Your lymph fluid is carried to your lymph nodes by lymphatic vessels. The lymph nodes filter out harmful substances and waste products. They also contain immune cells called lymphocytes that destroy bacteria and cancer cells.

The filtered fluid is then returned to your blood.

If you have an infection or cancer, a lymph node may become swollen. If you are concerned about your lymph nodes, speak to your doctor.

Your lymph nodes are located throughout your body. They drain lymph fluid from your nearby organs or areas of your body.

Lymph nodes (1)

What causes swollen lymph nodes?

Your lymph nodes may be swollen due to infection or inflammation. Swollen lymph nodes may be found in your neck, under the arms or anywhere else that there are lymph nodes.

Common causes of swollen lymph nodes are:

  • viruses (such as glandular fever)
  • bacterial infections (such as tonsillitis)
  • some autoimmune conditions

Your lymph nodes can swell up to several centimetres. They may stay swollen for several weeks after an infection.

Having swollen lymph nodes is very rarely a sign of cancer.

How are lymph nodes and cancer related?

Sometimes cancer can start in your lymph nodes (such as in lymphoma). Some other types of cancer can also spread from one part of your body to another through your lymph nodes.

Your lymph nodes play an important role in cancer including its diagnosis and treatment. They provide some information on your chance of recovery.

If you have cancer, your doctors will examine your lymph nodes carefully to see whether they are affected by cancer. They can do this by:

  • feeling the lymph nodes in your neck, armpits and groin
  • getting scans, for example a CT scan
  • taking a small piece of tissue (biopsy) of the lymph nodes near your cancer, and examining them under a microscope

These tests help doctors to work out the best treatment for you. They also tell the doctors if your cancer has spread.

Lymph nodes (2024)

FAQs

What stage of cancer do lymph nodes swell? ›

Cancer can also start in the lymph nodes. These are called lymphomas. "In general, cancers that have spread to the lymph nodes are typically stage 2 or 3," says Juan Santamaria, MD, Nebraska Medicine surgical oncologist. "Many of these cancers are still treatable and even curable at this stage.

What do swollen lymph nodes feel like? ›

Swollen lymph nodes are a sign that something is wrong somewhere in your body. When your lymph nodes first swell, you might notice: Tenderness and pain in the lymph nodes. Swelling that may be the size of a pea or kidney bean, or even larger in the lymph nodes.

Can touching lymph nodes make them swell? ›

Feeling a normal lypnh node will not make it larger. There are many reasons for enlarged lymph nodes, including other infections. It is a good idea a medical professional to check you for those.

What your lymph nodes are telling you? ›

Lymph nodes (also called lymph glands) are part of your immune system, and they let you know when your body is fighting an infection by becoming enlarged or sensitive to the touch. They also function as an early warning system for some types of cancer.

Can you survive cancer if it is in your lymph nodes? ›

Cancer in the lymph nodes is usually a sign that cancer is starting to spread, but it is often treatable. How serious it is will depend on many factors, such as the type of cancer, the rate at which it is growing, the person's overall health, and the treatment options available.

What is the life expectancy of someone with lymph node cancer? ›

More than 70 percent of people live longer than 5 years after their diagnosis. Your outlook depends on factors such as your overall health, age, and the type of non-Hodgkin's lymphoma you have. Your healthcare team can give you the best idea of what to expect.

What are the warning signs of lymphoma? ›

Signs and symptoms of lymphoma may include:
  • Fever.
  • Night sweats.
  • Fatigue.
  • Itchy skin.
  • Painless swelling of lymph nodes in the belly, neck, armpits or groin.
  • Pain in chest, abdomen or bones.
  • Losing weight without trying.
May 23, 2024

What can be mistaken for a swollen lymph node? ›

For example, what appears to be a swollen lymph node in your armpit can actually be a cyst caused by shaving or using antiperspirants. Another common type of lump that may appear in lymph glands is a lipoma—a noncancerous, smooth mass comprised of fatty tissue.

Can you have swollen lymph nodes but not sick? ›

Healthcare providers usually only worry about swollen lymph nodes when they enlarge for no apparent reason. If you have a large, swollen area but you're not feeling sick and you didn't recently have a cold, flu or other infection, see your healthcare provider.

Does drinking a lot of water help swollen lymph nodes? ›

Does drinking a lot of water help swollen lymph nodes? Drinking plenty of water can help avoid dehydration and promote good lymphatic system function.

Is it bad to push on swollen lymph nodes? ›

Do not squeeze, drain, or puncture a painful lump. Doing this can irritate or inflame the lump, push any existing infection deeper into the skin, or cause severe bleeding. Get extra rest.

What size lymph node is concerning? ›

Size: Cervical lymph nodes and axillary nodes are atypical if > 1 cm, as compared to supraclavicular > 0.5 cm, and inguinal nodes >1.5 cm.

How do I know if something is wrong with my lymph nodes? ›

Swollen lymph nodes will feel like soft, round bumps, and they may be the size of a pea or a grape. They might be tender to the touch, which indicates inflammation. In some cases, the lymph nodes will also look larger than usual. Lymph nodes appear in parallel on both sides of the body.

Can lymph nodes swell from stress? ›

While stress does not directly cause swollen lymph nodes, it can drastically affect other areas of your body. The consequences of unchecked stress can include more frequent illnesses — which can lead to trouble with your lymphatic system.

At what stage do lymph nodes swell? ›

Your lymph nodes get larger when more blood cells come to fight off an invading infection. They all essentially pile in, causing pressure and swelling. Often, the lymph nodes that swell will be close to the infection's site. That means if you have strep throat, you may develop swollen lymph nodes in your neck.

Does Stage 3 cancer involve lymph nodes? ›

Stage 3 usually means the cancer is larger. It may have started to spread into surrounding tissues and there are cancer cells in the lymph nodes nearby.

What cancer starts with swollen lymph nodes? ›

Cancer that starts in the lymph nodes is called lymphoma. You can read more about lymphoma in Hodgkin Lymphoma and Non-Hodgkin Lymphoma. More often, cancer starts somewhere else and then spreads to lymph nodes.

What stage is cancer in the lymph nodes stage 4? ›

Stage 4. Stage 4 is the most advanced stage of lymphoma. Lymphoma that has started in the lymph nodes and spread to at least one body organ outside the lymphatic system (for example, the lungs, liver, bone marrow or solid bones) is advanced lymphoma.

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