Isopropanol overdose (2024)

Isopropyl alcohol can be harmful if it is swallowed or gets in the eyes.

These products may contain isopropanol:

• Alcohol swabs
• Cleaning supplies
• Paint thinners
• Perfumes
• Rubbing alcohol

Other products may also contain isopropanol.

Symptoms of an isopropanol poisoning include:

• Acting or feeling drunk
• Slurred speech
• Stupor
• Uncoordinated movement
• Coma (decreased level of consciousness and lack of responsiveness)
• Unconsciousness
• Unpaired movements of the eyes
• Throat pain
• Abdominal pain
• Burns and damage to the clear covering of the front of the eye (cornea)
• Dizziness
• Headache
• Low body temperature
• Low blood pressure
• Low blood sugar
• Nausea and vomiting (may contain blood)
• Rapid heart rate
• Skin redness and pain
• Slowed breathing
• Urination problems (too much or too little urine)

Seek medical help right away. Do not make the person throw up unless poison control or your health care provider tells you to. If the isopropanol is on the skin or in the eyes, flush with lots of water for at least 15 minutes.

If the isopropanol was swallowed, give the person water or milk right away, unless a provider tells you not to. Do not give anything to drink if the person has symptoms that make it hard to swallow. These include vomiting, seizures, or a decreased level of alertness. If the person breathed in the isopropanol, move them to fresh air right away.

Have this information ready:

• Person's age, weight, and condition
• Name of the product (ingredients and strength, if known)
• Time it was swallowed
• Amount swallowed

Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

Take the container to the hospital with you, if possible.

The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.

Tests that may be done include:

• Blood and urine tests
• Chest x-ray
• Electrocardiogram (ECG)

Treatment may include:

• Fluids through a vein (by IV)
• Tube through the nose into the stomach to empty the stomach, if the person took more than one swallow and arrives within 30 to 60 minutes after swallowing it (especially in children)
• Dialysis (kidney machine) (in very rare cases)
  
• Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator)

How well someone does depends on the amount of poison swallowed and how quickly treatment is received. The faster someone gets medical help, the better the chance for recovery.

Drinking isopropanol will most likely make you very drunk. Recovery is very likely if a person does not swallow a large amount.

However, drinking large amounts can lead to:

• Coma and possibly brain damage
• Internal bleeding
• Breathing difficulty
• Kidney failure

It is dangerous to give a child a sponge bath with isopropanol to reduce a fever. Isopropanol is absorbed through the skin, so it can make children very sick.

Nelson ME. Toxic alcohols. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 136.

Olives TD, Ling LJ. The alcohols: ethylene glycol, methanol, isopropyl alcohol, and alcohol-related complications. In: Bakes KM, Buchanan JA, Moreira ME, Byyny R, Pons PT, eds. Emergency Medicine Secrets. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 71.

Last reviewed on: 11/2/2023

Reviewed by: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.