Implement Microsoft Sentinel and Microsoft Defender XDR for Zero Trust (2024)

  • Article
  • Applies to:
    Microsoft Sentinel in the Microsoft Defender portal, Microsoft Sentinel in the Azure portal

This solution guide walks through the process of setting up Microsoft extended detection and response (XDR) tools together with Microsoft Sentinel to accelerate your organization’s ability to respond to and remediate cybersecurity attacks.

Microsoft Defender XDR is an XDR solution that automatically collects, correlates, and analyzes signal, threat, and alert data from across your Microsoft 365 environment.

Microsoft Sentinel is a cloud-native solution that provides security information and event management (SIEM) and security orchestration, automation, and response (SOAR) capabilities. Together, Microsoft Sentinel and Microsoft Defender XDR provide a comprehensive solution to help organizations defend against modern attacks.

This guidance helps you mature your Zero Trust architecture by mapping the principles of Zero Trust in the following ways.

Zero Trust Principle Met by
Verify explicitlyMicrosoft Sentinel collects data from across the environment and analyzes threats and anomalies so that your organization, and any automation implemented, can act based on all available and verified data points.

 Microsoft Defender XDR provides extended detection and response across users, identities, devices, apps, and emails. Configure Microsoft Sentinel automation to use the risk-based signals captured by Microsoft Defender XDR to take action, such as blocking or authorizing traffic based on the level of risk.

Use least privileged accessMicrosoft Sentinel detects anomalous activity through its User Entity Behavioral Analytics (UEBA) engine. Since security scenarios can change over time, and often very quickly, Microsoft Sentinel's threat intelligence also imports data Microsoft or third-party providers to detect new, emerging threats and provide extra context for investigations.

 Microsoft Defender XDR has Microsoft Entra ID Protection, which can block users based on the level of risk with identity. Feed any related data into Microsoft Sentinel for further analysis and automation.

Assume breach Microsoft Defender XDR continuously scans the environment for threats and vulnerabilities. Microsoft Sentinel analyzes collected data and each entity's behavioral trends to detect suspicious activity, anomalies, and multi-stage threats across enterprise.

Both Microsoft Defender XDR and Microsoft Sentinel can implement automated remediation tasks, including automated investigations, device isolation, and data quarantine. Device risk can be used as a signal to feed into Microsoft Entra Conditional Access.

Microsoft Sentinel and XDR architecture

Microsoft Sentinel customers can use one of the following methods to integrate Microsoft Sentinel with Microsoft Defender XDR services:

This solution guide provides information for both methods. Throughout this solution guide, select the tab that's relevant for your workspace. If you've onboarded your workspace to the unified security operations platform, work in the Defender portal. If you haven't onboarded your workspace, work in the Azure portal unless otherwise indicated.

  • Defender portal
  • Azure portal

The following illustration shows how Microsoft's XDR solution seamlessly integrates with Microsoft Sentinel with the unified security operations platform.

In this diagram:

  • Insights from signals across your entire organization feed into Microsoft Defender XDR and Microsoft Defender for Cloud.
  • Microsoft Sentinel provides support for multicloud environments and integrates with third-party apps and partners.
  • Microsoft Sentinel data is ingested together with your organization's data into the Microsoft Defender portal.
  • SecOps teams can then analyze and respond to threats identified by Microsoft Sentinel and Microsoft Defender XDR in the Microsoft Defender portal.

Implementing Microsoft Sentinel and Microsoft Defender XDR for Zero Trust

Microsoft Defender XDR is an XDR solution that complements Microsoft Sentinel. An XDR pulls raw telemetry data from across multiple services like cloud applications, email security, identity, and access management.

Using artificial intelligence (AI) and machine learning, the XDR then performs automatic analysis, investigation, and response in real time. The XDR solution also correlates security alerts into larger incidents, providing security teams greater visibility into attacks, and provides incident prioritization, helping analysts understand the risk level of the threat.

With Microsoft Sentinel, you can connect to many security sources using built-in connectors and industry standards. With its AI you can correlate multiple low fidelity signals spanning multiple sources to create a complete view of ransomware kill chain and prioritized alerts.

Applying SIEM and XDR capabilities

In this section, we look into a typical attack scenario involving a phishing attack then proceed with how to respond to the incident with Microsoft Sentinel and Microsoft Defender XDR.

Common attack order

The following diagram shows a common attack order of a phishing scenario.

The diagram also shows the Microsoft security products in place to detect each attack step and how attack signals and SIEM data flow to Microsoft Defender XDR and Microsoft Sentinel.

Here's a summary of the attack.

Attack stepDetection service and signal sourceDefenses in place
1. Attacker sends phishing emailMicrosoft Defender for Office 365Protects mailboxes with advanced anti-phishing features that can protect against malicious impersonation-based phishing attacks.
2. User opens attachmentMicrosoft Defender for Office 365The Microsoft Defender for Office 365 Safe Attachments feature opens attachments in an isolated environment for more threat scanning (detonation).
3. Attachment installs malwareMicrosoft Defender for EndpointProtects endpoints from malware with its next generation protection features, such as cloud-delivered protection and behavior-based/heuristic/real-time antivirus protection.
4. Malware steals user credentialsMicrosoft Entra ID and Microsoft Entra ID ProtectionProtects identities by monitoring user behavior and activities, detecting lateral movement, and alerting on anomalous activity.
5. Attacker moves laterally across Microsoft 365 apps and dataMicrosoft Defender for Cloud AppsCan detect anomalous activity of users accessing cloud apps.
6. Attacker downloads sensitive files from a SharePoint folderMicrosoft Defender for Cloud AppsCan detect and respond to mass download events of files from SharePoint.

If you onboarded your Microsoft Sentinel workspace to the unified security operations platform, SIEM data is available with Microsoft Sentinel directly in the Microsoft Defender portal.

Incident response using Microsoft Sentinel and Microsoft Defender XDR

Now that we've seen how a common attack takes place, let's look into using the integration of Microsoft Sentinel and Microsoft Defender XDR for incident response.

Select the relevant tab for your workspace depending on whether you onboarded your workspace to the unified security operations platform.

  • Defender portal
  • Azure portal

After integrating Microsoft Sentinel and Microsoft Defender XDR by onboarding your workspace to the unified security operations platform, complete all incident response steps directly in the Microsoft Defender portal, just as you would for other Microsoft Defender XDR incidents. Supported steps include everything from triage to investigation and resolution.

Use the Microsoft Sentinel area in the Microsoft Defender portal for features unavailable with the Defender portal alone.

For more information, see Respond to an incident using Microsoft Sentinel and Microsoft Defender XDR.

Key capabilities

To implement a Zero trust approach in managing incidents, use these Microsoft Sentinel and XDR features.

Capability or featureDescriptionProduct
AIR capabilities are designed to examine alerts and take immediate action to resolve breaches. AIR capabilities significantly reduce alert volume, allowing security operations to focus on more sophisticated threats and other high-value initiatives.Microsoft Defender XDR
Advanced huntingAdvanced hunting is a query-based threat hunting tool that lets you explore up to 30 days of raw data. You can proactively inspect events on your network to locate threat indicators and entities. The flexible access to data enables unconstrained hunting for both known and potential threats.Microsoft Defender XDR
Custom file indicatorsPrevent further propagation of an attack in your organization by banning potentially malicious files or suspected malware.Microsoft Defender XDR
Cloud discoveryCloud Discovery analyzes traffic logs collected by Defender for Endpoint and assesses identified apps against the cloud app catalog to provide compliance and security information.Microsoft Defender for Cloud Apps
Custom network indicatorsBy creating indicators for IPs and URLs or domains, you can now allow or block IPs, URLs, or domains based on your own threat intelligence.Microsoft Defender XDR
Endpoint detection and response (EDR) BlockProvides added protection from malicious artifacts when Microsoft Defender Antivirus (MDAV) isn't the primary antivirus product and is running in passive mode. EDR in block mode works behind the scenes to remediate malicious artifacts that were detected by EDR capabilities.Microsoft Defender XDR
Device response capabilitiesQuickly respond to detected attacks by isolating devices or collecting an investigation packageMicrosoft Defender XDR
Live responseLive response gives security operations teams instantaneous access to a device (also referred to as a machine) using a remote shell connection. This gives you the power to do in-depth investigative work and take immediate response actions to promptly contain identified threats in real time.Microsoft Defender XDR
Secure cloud applicationsA development security operations (DevSecOps) solution that unifies security management at the code level across multicloud and multiple-pipeline environments.Microsoft Defender for Cloud
Improve your security postureA cloud security posture management (CSPM) solution that surfaces actions that you can take to prevent breaches.Microsoft Defender for Cloud
Protect cloud workloadsA cloud workload protection platform (CWPP) with specific protections for servers, containers, storage, databases, and other workloads.Microsoft Defender for Cloud
User and Entity Behavioral Analytics (UEBA)Analyzes behavior of organization entities such as users, hosts, IP addresses, and applications)Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

FusionA correlation engine based on scalable machine learning algorithms. Automatically detects multistage attacksalso known as advanced persistent threats (APT)by identifying combinations of anomalous behaviors and suspicious activities that are observed at various stages of the kill chain.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

Threat IntelligenceUse Microsoft third-party providers to enrich data to provide extra context around activities, alerts, and logs in your environment.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

AutomationAutomation rules are a way to centrally manage automation with Microsoft Sentinel, by allowing you to define and coordinate a small set of rules that can apply across different scenarios.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

Anomaly rulesAnomaly rule templates use machine learning to detect specific types of anomalous behavior.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

Scheduled queriesBuilt-in rules written by Microsoft security experts that search through logs collected by Sentinel for suspicious activity chains, known threats.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

Near-real-time (NRT) rulesNRT rules are limited set of scheduled rules, designed to run once every minute, in order to supply you with information as up-to-the-minute as possible. Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

HuntingTo help security analysts look proactively for new anomalies that weren't detected by your security apps or even by your scheduled analytics rules, Microsoft Sentinel's built-in hunting queries guide you into asking the right questions to find issues in the data you already have on your network.Microsoft Sentinel

For onboarded workspaces, use the Microsoft Defender portal's advanced hunting functionality.

Microsoft Defender XDR ConnectorThe Microsoft Defender XDR connector synchronizes logs and incidents to Microsoft Sentinel.Microsoft Defender XDR and Microsoft Sentinel br>
For onboarded workspaces, Microsoft Sentinel in the unified security operations platform
Data connectorsAllow for the ingestion of data for analysis in Microsoft Sentinel.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

Content hub solution -Zero Trust (TIC 3.0)Zero Trust (TIC 3.0) includes a workbook, analytics rules, and a playbook, which provide an automated visualization of Zero Trust principles, cross-walked to the Trust Internet Connections framework, helping organizations to monitor configurations over time.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

Security orchestration, automation, and response (SOAR)Using automation rules and playbooks in response to security threats increases your SOC's effectiveness and saves you time and resources.Microsoft Sentinel

For onboarded workspaces, Microsoft Sentinel in the unified security operations platform

SOC optimizationsClose coverage gaps against specific threats and tighten your ingestion rates against data that doesn't provide security value.

What's in this solution

This solution steps you through the implementation of Microsoft Sentinel and XDR so that your security operations team can effectively remediate incidents using a Zero Trust approach.

Recommended training

Training content doesn't currently cover the unified security operations platform.

TrainingConnect Microsoft Defender XDR to Microsoft Sentinel
Implement Microsoft Sentinel and Microsoft Defender XDR for Zero Trust (4)Learn about the configuration options and data provided by Microsoft Sentinel connectors for Microsoft Defender XDR.

Start >

Next steps

Use these steps to implement Microsoft Sentinel and XDR for a Zero Trust approach:

  1. Set up your XDR tools
  2. Architect your Microsoft Sentinel workspace
  3. Ingest data sources
  4. Respond to an incident

Also see these articles for applying Zero Trust principles to Azure:

  • Azure IaaS overview
  • Azure storage
  • Virtual machines
  • Spoke virtual networks
  • Hub virtual networks
  • Spoke virtual network with Azure PaaS Services
  • Azure Virtual Desktop
  • Azure Virtual WAN
  • IaaS applications in Amazon Web Services
Implement Microsoft Sentinel and Microsoft Defender XDR for Zero Trust (2024)

FAQs

How do I integrate Microsoft Defender and Microsoft Sentinel? ›

Sign in to the Azure portal and navigate to Microsoft Sentinel > Pick the relevant workspace to integrate with Microsoft Defender XDR. In the navigation pane, under Configuration, go to Data connectors. When the page loads, search for Microsoft Defender XDR and select the Microsoft Defender XDR connector.

What is the difference between Microsoft Defender XDR and Sentinel? ›

Microsoft Defender XDR continuously scans the environment for threats and vulnerabilities. Microsoft Sentinel analyzes collected data and each entity's behavioral trends to detect suspicious activity, anomalies, and multi-stage threats across enterprise.

What is XDR Sentinel? ›

Cross-Stack Data Correlation and Visibility

The best thing about SentinelOne XDR is that it ingests data from cross-domain and unifies them at one dashboard. As a result, it removes blind spots in your security system and lets your team see where vulnerabilities are lurking.

Does Microsoft have an XDR solution? ›

Microsoft Defender XDR is an XDR platform that provides security across your multiplatform endpoints, hybrid identities, emails, collaboration tools, and cloud apps.

Is Microsoft Defender EDR or XDR? ›

EDR systems, such as Microsoft Defender for Endpoint, provide a scalable security foundation that simplifies endpoint security management throughout your business.

What is the difference between Microsoft Sentinel and defender for cloud? ›

Whereas MDC is aimed at most members of an Azure administration and development team, Sentinel is intended for use by full-time information security professionals.

Is SentinelOne an XDR or EDR? ›

Leading the industry in XDR, SentinelOne's AI-Powered Singularity XDR Platform has all the benefits of a complete solution: deep visibility, automated detection and response, rich integration, and operational simplicity.

Why is XDR better than SIEM? ›

Extended Detection and Response (XDR) and Security Information and Event Management (SIEM) are both enterprise cybersecurity solutions. But while XDR and SIEM both pull and analyze data from multiple sources to detect cyber threats, XDR includes advanced cybersecurity functionality.

Why XDR is better than EDR? ›

The main differences between EDR and XDR are: Focus — EDR focuses on endpoint protection, providing detailed visibility and threat protection for specific devices. XDR takes a broader view and unifies security across endpoints, cloud computing, email and other solutions.

Does XDR replace antivirus? ›

To summarize, while antivirus software protects against some known malware, EDR and XDR provide a much stronger approach to the detection and response of some of today's most sophisticated threats. Antivirus will provide basic protection while EDR + XDR offers seamless threat detection and response.

What does XDR stand for? ›

XDR (extended detection and response) collects and automatically correlates data across multiple security layers – email, endpoint, server, cloud workload, and network. This allows for faster detection of threats and improved investigation and response times through security analysis. XDR.

Can XDR replace EDR? ›

Can XDR replace EDR? Yes, XDR solutions can replace EDR solutions by providing a more comprehensive and integrated approach to security. However, this may come at a higher cost and require more resources and expertise to manage effectively.

What is Microsoft Sentinel? ›

What is Microsoft Sentinel, and how does it work? Microsoft Sentinel is a cloud-native security information and event management (SIEM) platform that uses built-in AI to help analyze large volumes of data across an enterprise—fast.

What is the old name for Microsoft Defender XDR? ›

Microsoft Defender XDR (formerly Microsoft 365 Defender) is an industry-leading XDR platform.

What is the recommended first step for implementing zero trust security in Microsoft 365? ›

The first step is to build your Zero Trust foundation by configuring identity and device access protection.

How do I connect defender for cloud apps to Sentinel? ›

Integrating with Microsoft Sentinel
  • In the Microsoft Defender Portal, select Settings > Cloud Apps.
  • Under System, select SIEM agents > Add SIEM agent > Sentinel. ...
  • In the wizard, select the data types you want to forward to Microsoft Sentinel. ...
  • Select Next, and continue to Microsoft Sentinel to finalize the integration.
Jan 22, 2024

Do I need another antivirus if I have Microsoft Defender? ›

If you have Defender for Endpoint, you can benefit from running Microsoft Defender Antivirus alongside another antivirus solution. For example, Endpoint detection and response (EDR) in block mode provides added protection from malicious artifacts even if Microsoft Defender Antivirus isn't the primary antivirus product.

What do you use to provide real-time integration between Microsoft Sentinel and another? ›

Many connectors are packaged with SIEM solutions for Microsoft Sentinel and provide real-time integration. These connectors include Microsoft sources and Azure sources like Microsoft Entra ID, Azure Activity, Azure Storage, and more.

How to integrate Defender for Cloud apps with Defender for Identity? ›

Open Microsoft Defender portal > More resources > Microsoft Defender for Cloud Apps. 2. Click the gear in the top right corner > Settings > Microsoft Defender for Identity. Check the Enable Microsoft Defender for Identity integration.

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