EIP 6963: Multi Wallet Discovery
MetaMask now supports EIP 6963, which, when implemented by dapps, means you can choose which browser extension wallet you want to use. This addresses a situation where, without EIP 6963 implementation, wallets would compete to be identified.
This means the problem described above—multiple extension wallets being unable to peacefully coexist—should now become rarer. Naturally, though, this depends on the rate at which dapps build EIP 6963 into their sites.
Either way, you still cannot have multiple types of MetaMask active simultaneously in one browser profile. Read more here.