Filtration Market Size, Global Research Report, 2035 (2024)

Filtration Market Overview

The global filtration market size is estimated to grow from USD 5.1 billion in 2023 to USD 15 billion by 2035, representing a CAGR of 9% during the forecast period 2023-2035.

Biologics represents one of the fastest growing segments of the healthcare sector. In last five years, over 50 biologics been approved by the Food and Drug Administration (FDA) and close to 10,000 biologics are being evaluated across different stages of development. The growing demand for biologics has consequently led to the need for development of advanced technologies for the purification of these drug substances. This need is primarily driven by the fact that biologics are sensitive to heat and other chemically driven purification treatments, which may result in degradation of the final product.

Biopharmaceutical filtration refers to the process of purification and sterilization of biological drug products without the application of heat and chemicals. A key advancement in this industry has been the introduction of novel filtration systems, such as depth filtration, tangential flow filtration, virus filtration and chromatography filtration systems. These systems can be applied to a wide variety of application areas due to their flexible nature. In fact, several large pharma companies have already made investments and technological advancements to improve their conventional filtration technologies. The primary goal behind introducing these filters is to achieve the highest possible purity and yield of the desired biological product, along with maintaining its safety and efficacy for use in human or animal health. Given the ongoing advancements in the nature of biologics, several companies have developed and launched their proprietary biopharmaceutical filtration systems for more efficient purification of biologics. Overall, the global filtration market growth is expected to be driven by the rising demand for biologics.

Filtration MarketKey Market Insights

The Filtration Market (Focus on Biologics Manufacturing) - Distribution by Type of Filtration System (Depth Filtration, Tangential Flow Filtration, Virus Filtration and Other Membrane Filters), Type of Filter (based on use) (Disposable / Single use Filters and Reusable / Multi use Filters), Type of Assembly (Capsules, Cartridges and Others), Company Size (Small, Mid-sized and Large) and Key Geographical Regions (North America, Europe, Asia-Pacific and Rest of the World): Industry Trends and Global Forecasts, 2023-2035 market report features an extensive study of the competitive landscape, market size and future opportunities associated with companies manufacturing biopharmaceutical filtration systems, during the given forecast period. The global filtration market report highlights the efforts of several stakeholders engaged in this emerging and rapidly evolving segment of the biopharmaceutical industry. Key takeaways from the study of filtration market are briefly discussed below.

Biopharmaceutical Filtration Systems: Benefits and Growing Demand for Tangential Flow Filtration and Depth Filtration Systems

Biopharmaceutical filtration systems are used to separate and purify biological products, such as proteins, antibodies and vaccines. Depth filtration and tangential flow filtration systems offer several benefits over conventional systems, such as higher efficiency, enhanced product purity and higher throughput. Driven by these benefits, the demand for efficient depth filtration and tangential flow filtration systems is anticipated to increase, resulting in lucrative opportunities for developers. In November 2022, High Purity New England (HPNE) launched their OptiMaxx TFF system for downstream bioprocessing applications. This off-the-shelf TFF system is optimized for cGMP low volume manufacturing. Another company, Verdot launched its single use TFF system in September 2023, driven by customer demand.

Current Market Landscape: Several Companies Operating in the Membrane Filtration Market

The competitive landscape of biopharmaceutical filter manufacturers features a mix of over 80 large, mid-sized and small companies, which have the required expertise to offer various depth filtration systems, tangential flow filtration systems, virus filtration systems and chromatography filtration systems, across different scales of operation. It is worth mentioning that more than 80% of the companies have the ability to develop membrane filtration systems. Further, the ongoing activity in filtration industry indicates that biopharmaceutical filtration system manufacturers are continuously upgrading their capabilities and infrastructure to accommodate the current and anticipated future demand for protein purification.

Key Drivers Behind the Biopharmaceutical Filtration Market

The biopharmaceutical industry has rapidly expanded over the years, primarily driven by increasing prevalence of chronic diseases and rising demand for regenerative therapies and personalized medicines. This has, in turn, led to a subsequent escalation in demand for depth filtration systems, tangential flow filtration systems and virus filtration systems for processing of biologics. Further, the stringent government regulations and guidelines, such as Good Manufacturing Practices (GMP) and United States Pharmacopeia (USP) standards, established to ensure product safety and quality, has created a need for technological advancements in filtration global market. It is also worth highlighting that, adoption of single use technologies, and development of new and advanced filtration systems, such as tangential flow filtration, chromatography filtration and virus filtration, are likely to create new opportunities in the market. Over the forecast period, we expect the filter manufacturers to continue to develop solutions that cater to the needs of complex biologic manufacturers, driving the global filtration market growth.

Market Size of the Biopharmaceutical Filtration Market: Membrane Filtration to Drive the Market Growth over the Forecast Period

Driven by the rapid growth of the biopharmaceutical industry and increasing research and development activities, the future opportunities and growth associated with the filtration market for biologics is anticipated to witness a noteworthy growth in the foreseen future. Specifically, in terms of type of filter, the market is anticipated to be driven by membrane filtration system, followed by depth filtration system and tangential flow filtration system. The membrane filtration market size is estimated to be $2.3 billion in 2023 and is projected to grow at a CAGR of 7%, during the forecast period. Further, more than 60% of the market is anticipated to be represented by companies based in North America and Europe, in the foreseen future.

Biopharmaceutical Filtration Companies are Investing in Facility Expansions to Meet the Growing Demand

A number of companies are expanding their facilities to gain either new capabilities or increase the capacity. In June 2023, Parker Hannifin announced to invest multimillion-dollar to strengthen its biopharmaceutical filtration capabilities in Birtley, UK Site. In May 2023, 3M announced the investment of around $150 million for the expansion of existing capabilities and facilities in Europe. The expansion is anticipated to accelerate 3M's plan for the development and delivery of pharmaceutical and biopharma filtration systems.

Key Players in the Filtration Market

Examples of key players engaged in biopharmaceutical filtration industry (which have also been captured in this report) include Alfa Laval, Asahi Kasei, Cobetter Filtration, Corning, Merck KGaA, Pall Corporation (a company of Danaher Corporation), Parker Hannifin, Sartorius and Thermo Fisher Scientific. This global filtration market report includes an easily searchable excel database of all the companies providing filtration systems to support biologics manufacturing, worldwide.

Recent Developments in Filtration Market

Several recent developments have taken place in the field of biopharmaceutical filtration. We have outlined some of these recent initiatives below. These developments, even if they took place post the release of our market report, substantiate the overall market trends that we’ve outlined in our filtration market analysis.

• In February 2023, Danahar acquired Isolere bio in order to advance the manufacturing and purification of pharmaceuticals.
• In January 2023, Sartorius entered into a collaboration with RoosterBio for the advancement of downstream purification processes to manufacture exosomes. Under the collaboration, both the companies will develop scalable platform purification processes using Sartorius’ comprehensive toolbox of solutions. In order to develop these purification methods, Sartorius will use its scalable filtration equipment Sartoflow® Smart and Sartoflow® Advanced.

Scope of the Filtration MarketReport

The study presents an in-depth analysis of the various firms / organizations that are engaged in the global filtration industry, across different segments as defined in the below table:

The global filtration market research presents an in-depth analysis, highlighting the capabilities of various stakeholders engaged in this industry, across different geographies. Amongst other elements, the market report includes:

• An executive summary of the insights captured during our research. It offers a high-level view on the current state of biopharmaceutical filtration market and its likely evolution in the mid-long term.
• A general overview of filtration systems, highlighting details on different types of filtration systems (depth filtration systems, tangential flow filtration systems, virus filtration systems and membrane filtration systems) and steps involved in sterile filtration for bioprocessing. It also presents information on the factors affecting sterile filtration, advantages of biopharmaceutical filtration systems, challenges associated with biopharmaceutical filtration systems and applications of biopharmaceutical filtration. Additionally, it presents an overview of the ongoing market trends and future outlook for the biopharmaceutical filtration industry.
• A detailed assessment of the overall competitive landscape of companies offering biopharmaceutical filtration systems, based on several relevant parameters, such as year of establishment, company size (in terms of number of employees), location of headquarters, type of filter system / element (depth filtration systems, tangential flow filtration systems, virus filtration systems and membrane filtration systems) and application area (viral clearance, cell culture clarification, cell separation / protein purification, sterilization and others). In addition, it includes information on type of filter (based on use) (disposable or single use and reusable or multi use), type of filter module (encapsulated), type of media material (natural components, synthetic, polypropylene or glass microfiber), type of assembly (pod, capsule, cassette, hollow fibre, and others), novel filtration systems offered (chromatography filtration and tangential flow depth filtration) and type of technique used (ultrafiltration, microfiltration and nanofiltration).
• A detailed competitiveness analysis of biopharmaceutical filtration system manufacturers based in North America, Europe and Asia-Pacific, based on supplier strength (in terms of years of experience, company size and number of filter system / element offered), product strength (considering features of depth filtration systems, tangential flow filtration systems, virus filtration systems and membrane filtration systems, novel filtration systems, type of technique used) and application areas (viral clearance, cell culture clarification, cell separation / protein purification, sterilization and others).
• Tabulated profiles of key players based in North America, Europe and Asia-Pacific that are engaged in manufacturing biopharmaceutical filtration systems (shortlisted based on company size and availability of financial information). Each profile includes a brief overview of the company, details related to its financial information (if available), product portfolio, recent developments and an informed future outlook.
• An in-depth analysis of recent developments / trends in the biopharmaceutical filtration market, offering insights on patents that have been filed / granted for biopharmaceutical filters, since 2019, based on relevant parameters, such patent publication year, patent jurisdiction, CPC symbols, emerging focus areas, leading players (in terms of number of patents granted), patent benchmarking (in terms of CPC codes and leading players), patent characteristics and patent age. It also includes an insightful patent valuation analysis and list of leading patents based on number of citations. In addition, it provides information on recent mergers and acquisitions reported in global filtration market, including details on year, deal amount, regional distribution and key players (in terms of number of deals).
• A detailed analysis of global events that took place in the global filtration market, since 2018 based on several relevant parameters, such as year of event, event platform, type of event, geography, type of filter (based on use) (single use and reusable filters), type of filter system involved (depth filtration systems, tangential flow filtration systems, virus filtration systems and membrane filtration systems, sterilizing grade filters, and others), type of process involved (upstream bioprocessing and single use downstream bioprocessing), most active organizers (in terms of number of events) and application area (type of biologic involved), as well as prominent players.

One of the key objectives of the filtration market report was to estimate the current opportunity and the future growth potential of the biopharmaceutical filtration market over the coming years. We have provided informed estimates on the likely evolution of the market for the period, 2023-2035. Our year-wise projections of the current and forecasted opportunity have been further segmented based on relevant parameters, such as type of filter system / element (depth filtration systems, tangential flow filtration systems, virus filtration systems and membrane filtration systems), type of filter (based on use) (disposable / single use filters and reusable / multi use filters), type of assembly (capsules, cartridges and others), company size (small, mid-sized and large) and key geographical regions (North America, Europe, Asia-Pacific and Rest of the World). In order to account for future uncertainties associated with some of the key parameters and to add robustness to our model, we have provided three market forecast scenarios, portraying the conservative, base and optimistic tracks of the industry’s evolution.

All actual figures have been sourced and analyzed from publicly available information forums and primary research discussions. Financial figures mentioned in this report are in USD, unless otherwise specified.

Frequently Asked Questions

Question 1: What is filtration in pharmaceutical industry?

Answer: Filtration involves the separation of active ingredients from the culture media, cell debris and other impurities.

Question 2: How many types of filtration systems are there in the pharmaceutical industry?

Answer: In the pharmaceutical industry, various types of filtration systems are used; examples include depth filtration systems, tangential flow filtration systems, virus filtration systems, other membrane filtration systems and chromatography filtration systems.

Question 3: What are the limitations of conventional filtration systems?

Answer: Limited filtration capacity, need for frequent maintenance, risk of clogging, and limited lifespan are the common limitations.

Question 4: How many companies are operating in the biopharmaceutical filtration market?

Answer: Presently, more than 80 companies are involved in the development of depth filtration system, tangential flow filtration system, virus filtration system and other membrane filtration system.

Question 5: How many patents, related to biopharmaceutical filtration, have been filed / granted in the last few years?

Answer: Close to 130 patents have been filed / granted related to biopharmaceutical filtration, in the last few years.

Question 6: What are the key biopharmaceutical filtration market trends?

Answer: Significant investments have been made in expansion of existing capabilities through the incorporation of advanced methods, technologies and platforms.

Question 7: Which industries use membrane filtration?

Answer: Membrane filtration is used for chemical and metal processing, pharmaceuticals, water treatment, food industry, biotechnology, and removal of environmental pollutants.

Question 8: How big is the biopharmaceutical filtration market?

Answer: The global filtration market size for biologics is likely to be worth $5.1 billion in 2023.

Question 9: What is the anticipated biopharmaceutical filtration market growth rate?

Answer: The biopharmaceutical filtration market is projected to grow at a CAGR of ~10% in the coming years.

Question 10: How big is the membrane filtration market?

Answer: The membrane filtration market size is estimated to be $2.3 billion in 2023.

Question 11: What is the anticipated membrane filtration market growth rate?

Answer: The membrane filtration market value is projected to grow at a CAGR of 7%, during the forecast period.